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Rated 1.7 out of 5
Based on 3 reviews

Dermalogica Phyto Nature E² Regenerating Daily Exosome Leave-on Treatment

A daily leave-on that exfoliates and smooths in one step, with a plant exosome blend for the look of fine lines. Dermalogica Phyto Nature E²... learn more

$266.00

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Description

A daily leave-on that exfoliates and smooths in one step, with a plant exosome blend for the look of fine lines. Dermalogica Phyto Nature E² Regenerating Daily Exosome Leave-on Treatment is a lightweight liquid made with plant-derived exosomes, pumpkin ferment enzymes and acacia gum. It smooths, brightens and hydrates, and is gentle enough for sensitive, mature or menopausal skin. A good fit for dry, dull or sensitised skin, and for nights off retinol.

How to Use

After cleansing, press 2–3 pumps gently into skin. Follow with moisturiser, and SPF in the morning. If you use a retinoid, use E² on alternate nights.

Benefits

Phyto Nature E² pairs plant-derived exosomes from turmeric with a pumpkin ferment exfoliant and firming botanicals. Exosomes are tiny parcels that cells use to pass messages to each other. In skincare they come from plants, and the research is early: most of it is lab work so far. In Dermalogica's independent clinical study of 32 people using it twice a day, fine lines and wrinkles looked visibly diminished in 2 weeks.

Pumpkin ferment exfoliates gently by breaking down dead surface skin cells, without the sting of acids, so it suits skin that's dry, flaky or tired of retinol. Acacia gum gives an instant tightening feel for a subtle lift, and acetyl glucosamine helps keep skin hydrated.

Use it as a prep step after cleansing if your skin is changing with hormones, feeling dry or stressed, or you just want a simpler routine that does more.

Ingredients

Water/Aqua/Eau, Glycerin, Butylene Glycol, Lactobacillus/Pumpkin Fruit Ferment Filtrate, Acetyl Glucosamine, Propanediol, Sodium Hyaluronate Crosspolymer, Hydrolyzed Sodium Hyaluronate, Prickly Pear Cactus Extract, Curcuma Longa (Turmeric) Callus Conditioned Media, Acacia Senegal Gum, Glycogen, Betaine, Saccharide Isomerate, Caprylyl Glycol, Ethylhexylglycerin, 1,2-Hexanediol, Hydroxyacetophenone, Citric Acid, Xanthan Gum, Sodium Citrate, Biosaccharide Gum-1, Disodium EDTA, Parfum/Fragrance.

What is it good for?

A leave-on liquid treatment that exfoliates gently, with plant-derived exosomes, for visibly smoother, brighter, firmer-looking skin.

Instantly smooths and softens with enzymatic exfoliation

Reduces the look of tiredness for a more radiant glow

Gentle on the skin barrier, a good fit for post-retinol skin

Instantly smooths and softens with enzymatic exfoliation

Reduces the look of tiredness for a more radiant glow

Hydrates, with botanicals for a firmer look

What's inside?

A blend of botanicals, gentle enzymes and hydrators to smooth, brighten and refresh the look of skin.

Turmeric Exosomes

Plant-derived exosomes from turmeric, with antioxidant benefits. Helps skin look calmer and more resilient.

Plant-derived exosomes from turmeric, with antioxidant benefits. Helps skin look calmer and more resilient.

Pumpkin Ferment Enzymes

A gentle exfoliant that works on dead surface skin cells, leaving skin smoother and more radiant without stripping.

A gentle exfoliant that works on dead surface skin cells, leaving skin smoother and more radiant without stripping.

Acacia Senegal Gum

Forms a fine film on the skin's surface for a subtle lifting, tightening feel.

Forms a fine film on the skin's surface for a subtle lifting, tightening feel.

Prickly Pear Extract

Rich in vitamins, polyphenols and fatty acids. Helps skin hold moisture and look more supple and radiant.

Rich in vitamins, polyphenols and fatty acids. Helps skin hold moisture and look more supple and radiant.

Reviews

average rating 1.7 out of 5
Based on 3 reviews
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0% of reviewers would recommend this product to a friend
Aroma/Scent
Rated 3 out of 5
Texture on Skin
Rated 4 out of 5
Value for Money
Rated 1 out of 5
3 Reviews
Reviewed by Georgena
Verified Reviewer
I don't recommend this product
Rated 2 out of 5
Review posted

30 years

Can I use for age 30 years?

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Was this helpful?

GLO Skin Body

Hi Georgena, Yes you can use this products if you are in your 30's. Please reach out to us if you require any further assistance.

Reviewed by khatija h.
Verified Buyer
I don't recommend this product
Age Range
35 - 44
Skin Concerns
  • Ageing
Did you notice a difference in your skin?
No
Rated 1 out of 5
Review posted

Not worth the price

Haven’t noticed any difference to my skin…in fact, I think that the fine lines are more prominent since I started using this product with the oxygen cream and cleanser than with the product I previously used

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Aroma/Scent
Rated 3 out of 5
Texture on Skin
Rated 4 out of 5
Value for Money
Rated 1 out of 5
Was this helpful?

GLO Skin Body

Thank you for taking the time to share your feedback. We understand it can be disappointing not to see the results you were hoping for.

Whilst the Phyto Nature E² can take time to deliver visible improvements, there are also other factors we like to consider. The formula encourages skin renewal, and during the cooler months this can sometimes highlight underlying dehydration, making fine lines appear more noticeable temporarily.
As every skin is different, we'd love the opportunity to review your skincare routine and ensure the product is the right fit for your skin's current needs. Please feel free to contact our team so we can provide personalised advice and help you achieve the best possible results.

Reviewed by KCHERIE
Verified Buyer
I don't recommend this product
Rated 2 out of 5
Review posted

An expensive product to play "will it, wont it" work!

To give this review context I have aging sensitive skin that is dry on the cheekbones, normal/oily in the t-zone and normal for the rest of the face. I have been using Dermalogica products for over twelve years so when I read the description on Dermalogica's new Phyto Nature E² I thought perfect this sounds like it would cover all the concerns my skin has.

After the first week I noticed no difference, it didn't effect my sensitivity as promised, but my face also didn't feel smoother to the touch.

I have now been using the product for almost two months - when I do my skincare I pre-cleanse, cleanse, use toner, the serum then moisturise every morning and night, its my way of winding down at night and feeling clean after the day had past, in addition when I use serum I rub the left over product into my elbows so its not wasted (I do the same for the moisturiser) and at night when I go to bed i also moisturise my elbows with a sensitive body moisturiser (I have been doing this for years) - when I was doing that I started to notice that my elbows have dry skin patches the size of a twenty cent piece on them, I dismissed it thinking I had been in a lot of air conditioned buildings and that doesn't help but as I started to be more conscience of this I realised that my cheekbones that I have had a problem with dryness are feeling dryer and the serum does not appear to be helping them.

I will state the the t-zone has been okay but the rest of my face feels drier to the point…

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GLO Skin Body

Hi K,Cherie,

Thank you for taking the time to share such a detailed and thoughtful review.

We’re sorry to hear that the Phyto Nature E² Regenerating Treatment hasn’t been the right fit for your skin, particularly given your long-standing experience with Dermalogica. We truly appreciate the context you’ve provided around your skin type and routine, it’s incredibly helpful.

From what you’ve described, it sounds like your skin may not have responded as expected to this formulation, particularly in terms of hydration and barrier support, which is so important for sensitive and drier areas. While this product is designed to target multiple concerns, some skins, especially those that are more delicate or lipid-dry, may require a more intensive barrier-repair approach rather than a multi-correction treatment.

We also appreciate you noting the changes not only on your face but on areas like your elbows, this kind of awareness is so valuable and clearly shows how in tune you are with your skin.

It’s completely understandable that you’ve returned to your UltraCalming Serum, as this range is specifically designed to support sensitivity and barrier health, which may be more aligned with what your skin is currently needing.

Your feedback is incredibly valuable, particularly for clients with similar skin types considering this product. If you would like to reach out to hello@skinmart.com.au as Dermalogica has a satisfactory guarantee.

Thank you again for your honesty and for sharing your experience so thoroughly.

Questions