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Rated 2.0 out of 5
Based on 1 review

Dermalogica Phyto Nature E² Regenerating Daily Exosome Leave-on Treatment

A next-gen bioactive serum that resurfaces and regenerates in one step.   Dermalogica Phyto Nature E² Regenerating Daily Exosome Leave-on Treatment is a daily leave-on liquid... learn more

$266.00

Preorders due to be dispatched within 3-4 business days

Description

A next-gen bioactive serum that resurfaces and regenerates in one step.   Dermalogica Phyto Nature E² Regenerating Daily Exosome Leave-on Treatment is a daily leave-on liquid treatment powered by plant-derived exosomes, pumpkin enzymes, and firming botanicals.   It smooths, brightens and revitalises while respecting sensitive, ageing or menopausal skin. Ideal for dry, dull, sensitised or post-retinol skin.

How to Use

Apply Phyto Nature E² Regenerating Daily Exosome Leave-on Treatment – 2–3 pumps pressed gently into skin. This lightweight liquid absorbs quickly to infuse exosomes and enzymes, supporting cell renewal and calming irritation.

How it Works

This isn’t just skincare – it’s cellular coaching. Phyto Nature E² Regenerating Daily Exosome Leave-on Treatment uses botanical exosomes from turmeric and acacia to help your skin behave younger, visibly reversing signs of biological ageing. These plant-derived messengers enter skin cells, easing inflammation, increasing resilience, and boosting radiance over time.

Pumpkin ferment delivers instant glow by gently digesting dead skin without the harshness of acids, making it perfect for those who are fatigued by retinol or struggle with dryness and flaking. Acacia gum tightens instantly for a subtle lift, while acetyl glucosamine supports hydration from within.

Whether you’re navigating hormonal skin shifts, calming inflammation, or simply want better performance from your routine, Phyto Nature E2 fits in seamlessly as a ‘prep and treat’ booster step. Think of it as a reset for stressed, tired skin – the new must-have for menopausal skin, barrier-compromised users or the “skintellectual” minimalist.

Ingredients

Water/Aqua/Eau, Lactobacillus/Pumpkin Ferment Extract, Propanediol, Lactococcus Ferment Lysate, Ethoxydiglycol, Hydrolyzed Soy Protein, Acetyl Glucosamine, Hydroxyacetophenone, Lactic Acid, Hydrolyzed Opuntia Ficus-Indica Flower Extract, Helianthus Annuus (Sunflower) Seed Oil, Citrus Aurantium Bergamia (Bergamot) Fruit Oil, Citrus Limon (Lemon) Peel Oil, Citrus Aurantium Dulcis (Orange) Peel Oil, Salvia Sclarea (Clary) Oil, Pyrus Malus (Apple) Fruit Extract, Viola Odorata Leaf Extract, Acacia Senegal Gum Extract, Curcuma Longa (Turmeric) Root Extract, Mucor Miehei Extract, Lavandula Spica (Lavender) Flower/Leaf/Stem Extract, Rosmarinus Officinalis (Rosemary) Leaf Oil, Litsea Cubeba Fruit Oil, Camellia Japonica Flower Extract, Glycerin, Mentha Piperita (Peppermint) Oil, Butylene Glycol, Lactobacillus Ferment, Glycogen, Urea, Caprylyl Glycol, Phospholipids, Glucosamine HCl, Xanthan Gum, PEG-40 Hydrogenated Castor Oil, 1,2-Hexanediol, Tetrasodium Glutamate Diacetate, Sodium Hydroxide, Citric Acid, Polyacrylate Crosspolymer-6, Acacia Senegal Gum, Sodium Chloride, Sodium Citrate, Disodium EDTA, Sodium Benzoate, Potassium Sorbate, Limonene, Linalool, Citral.Water/Aqua/Eau, Glycerin, Butylene Glycol, Lactobacillus/Pumpkin Fruit Ferment Filtrate, Acetyl Glucosamine, Propanediol, Sodium Hyaluronate Crosspolymer, Hydrolyzed Sodium Hyaluronate, Prickly Pear Cactus Extract, Curcuma Longa (Turmeric) Callus Conditioned Media, Acacia Senegal Gum, Glycogen, Betaine, Saccharide Isomerate, Caprylyl Glycol, Ethylhexylglycerin, 1,2-Hexanediol, Hydroxyacetophenone, Citric Acid, Xanthan Gum, Sodium Citrate, Biosaccharide Gum-1, Disodium EDTA, Parfum/Fragrance.

Shipping & Returns

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Order by 4pm (Sydney time) and we will dispatch same business day.

98% of our parcels are delivered on-time, but delays do occasionally happen across our large country. Shipping timeframes are an estimate only.

Buy with Confidence: Satisfaction guaranteed when professionally prescribed.

What is it good for?

A skin-renewing liquid treatment that exfoliates and regenerates with plant-derived exosomes for visibly smoother, brighter, firmer skin.

29285807-2C6C-4FC0-B82E-A81A623551A2

Anti Ageing

Rejuvenating

Skin Brightening

Smoothing skin

Softening Lines

Instantly smooths and softens with enzymatic exfoliation

Reduces signs of stress and fatigue for a more radiant glow

Strengthens skin barrier without irritation – perfect post-retinol or post-treatment

Instantly smooths and softens with enzymatic exfoliation

Reduces signs of stress and fatigue for a more radiant glow

Firms and hydrates with bio-lifting botanical actives

What's inside?

A bioactive blend of regenerative botanicals, gentle enzymes and skin-replenishing actives designed to smooth, brighten and restore visible vitality.

Turmeric Stem Cell Exosomes

Deliver potent antioxidant and anti-inflammatory actives to help restore resilience, reduce redness, and modulate ageing pathways linked to stress and hormonal shifts.

Deliver potent antioxidant and anti-inflammatory actives to help restore resilience, reduce redness, and modulate ageing pathways linked to stress and hormonal shifts.

Pumpkin Ferment Enzymes

A gentle, self-limiting exfoliant that digests only dead skin cells—no irritation, no over-stripping—leaving skin instantly smoother and more radiant.

A gentle, self-limiting exfoliant that digests only dead skin cells—no irritation, no over-stripping—leaving skin instantly smoother and more radiant.

Acacia Senegal Gum

Forms an invisible mesh on the skin’s surface, providing a subtle lifting and tightening effect while also soothing sensitivity.

Forms an invisible mesh on the skin’s surface, providing a subtle lifting and tightening effect while also soothing sensitivity.

Prickly Pear Extract

Rich in vitamins, polyphenols and essential fatty acids, this hydrating extract improves skin elasticity, reduces transepidermal water loss, and enhances glow.

Rich in vitamins, polyphenols and essential fatty acids, this hydrating extract improves skin elasticity, reduces transepidermal water loss, and enhances glow.

Dermalogica Phyto Nature E² Regenerating Daily Exosome Leave-on Treatment Dermalogica Phyto Nature E² Regenerating Daily Exosome Leave-on Treatment

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Read what the skin experts have to say:

Reviews

average rating 2.0 out of 5
Based on 1 review
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1 Review
Reviewed by KCHERIE
Verified Buyer
I don't recommend this product
Rated 2 out of 5
Review posted

An expensive product to play "will it, wont it" work!

To give this review context I have aging sensitive skin that is dry on the cheekbones, normal/oily in the t-zone and normal for the rest of the face. I have been using Dermalogica products for over twelve years so when I read the description on Dermalogica's new Phyto Nature E² I thought perfect this sounds like it would cover all the concerns my skin has.

After the first week I noticed no difference, it didn't effect my sensitivity as promised, but my face also didn't feel smoother to the touch.

I have now been using the product for almost two months - when I do my skincare I pre-cleanse, cleanse, use toner, the serum then moisturise every morning and night, its my way of winding down at night and feeling clean after the day had past, in addition when I use serum I rub the left over product into my elbows so its not wasted (I do the same for the moisturiser) and at night when I go to bed i also moisturise my elbows with a sensitive body moisturiser (I have been doing this for years) - when I was doing that I started to notice that my elbows have dry skin patches the size of a twenty cent piece on them, I dismissed it thinking I had been in a lot of air conditioned buildings and that doesn't help but as I started to be more conscience of this I realised that my cheekbones that I have had a problem with dryness are feeling dryer and the serum does not appear to be helping them.

I will state the the t-zone has been okay but the rest of my face feels drier to the point…

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GLO Skin Body

Hi K,Cherie,

Thank you for taking the time to share such a detailed and thoughtful review.

We’re sorry to hear that the Phyto Nature E² Regenerating Treatment hasn’t been the right fit for your skin, particularly given your long-standing experience with Dermalogica. We truly appreciate the context you’ve provided around your skin type and routine, it’s incredibly helpful.

From what you’ve described, it sounds like your skin may not have responded as expected to this formulation, particularly in terms of hydration and barrier support, which is so important for sensitive and drier areas. While this product is designed to target multiple concerns, some skins, especially those that are more delicate or lipid-dry, may require a more intensive barrier-repair approach rather than a multi-correction treatment.

We also appreciate you noting the changes not only on your face but on areas like your elbows, this kind of awareness is so valuable and clearly shows how in tune you are with your skin.

It’s completely understandable that you’ve returned to your UltraCalming Serum, as this range is specifically designed to support sensitivity and barrier health, which may be more aligned with what your skin is currently needing.

Your feedback is incredibly valuable, particularly for clients with similar skin types considering this product. If you would like to reach out to hello@skinmart.com.au as Dermalogica has a satisfactory guarantee.

Thank you again for your honesty and for sharing your experience so thoroughly.

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